- 专利标题： TRICYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS
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申请号： US17057875申请日： 2019-05-31
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公开(公告)号： US20210309671A1公开(公告)日： 2021-10-07
- 发明人: Tao YU , Alan WHITEHEAD , Yili CHEN , Chunrui SUN , Zhiyong HU , Kake ZHAO , Ronald M. KIM , John A. McCAULEY
- 申请人： Tao Yu , Alan Whitehead , Yili Chen , Chunrui Sun , Zhiy-ong Hu , Kake Zhao , Ronald M. Kim , John A. McCauley , MERCK SHARP & DOHME CORP.
- 申请人地址： US NJ Kenilworth; US NJ Rahway; US NJ Kenilworth; US NJ Kenilworth; US NJ Kenilworth; US NJ Kenilworth; US NJ Kenilworth; US NJ West Point; US NJ Rahway
- 专利权人： Tao Yu,Alan Whitehead,Yili Chen,Chunrui Sun,Zhiy-ong Hu,Kake Zhao,Ronald M. Kim,John A. McCauley,MERCK SHARP & DOHME CORP.
- 当前专利权人： Tao Yu,Alan Whitehead,Yili Chen,Chunrui Sun,Zhiy-ong Hu,Kake Zhao,Ronald M. Kim,John A. McCauley,MERCK SHARP & DOHME CORP.
- 当前专利权人地址： US NJ Kenilworth; US NJ Rahway; US NJ Kenilworth; US NJ Kenilworth; US NJ Kenilworth; US NJ Kenilworth; US NJ Kenilworth; US NJ West Point; US NJ Rahway
- 国际申请： PCT/US2019/034783 WO 20190531
- 主分类号： C07D498/22
- IPC分类号： C07D498/22 ; C07D471/16 ; C07D491/22 ; A61K45/06 ; A61P31/18
摘要：
The present invention relates to Tricyclic Heterocycle Compounds of Formula (I): (I) and pharmaceutically acceptable salts or prodrug thereof, where-in R1, R2, R3, R4, R5, R6 and n are as defined herein. The present invention also relates to compositions comprising at least one Tricyclic Heterocycle Compound, and methods of using the Tricyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.
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