Invention Application
- Patent Title: ACE2-Fc Trap
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Application No.: US16880804Application Date: 2020-05-21
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Publication No.: US20210284716A1Publication Date: 2021-09-16
- Inventor: Kayvan Niazi , C. Anders Olson , Shiho Tanaka , John H. Lee , Wendy Higashide , Patrick Soon-Shiong
- Applicant: ImmunityBio, Inc.
- Applicant Address: US CA Culver City
- Assignee: ImmunityBio, Inc.
- Current Assignee: ImmunityBio, Inc.
- Current Assignee Address: US CA Culver City
- Main IPC: C07K14/81
- IPC: C07K14/81
Abstract:
An ACE2-Fc hybrid construct is used as a therapeutic and/or analytic entity to treat an individual infected with a coronavirus or to detect a coronavirus in an analyte. In selected embodiments, the Fc portion of the hybrid construct is an IgA Fc portion, and in still further embodiments the ACE2 portion has a mutation that reduces or abolishes ACE2 catalytic activity.
Information query
