- 专利标题： PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF
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申请号： US16892786申请日： 2020-06-04
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公开(公告)号： US20200299246A1公开(公告)日： 2020-09-24
- 发明人: Geoff T. Halvorsen , Jennifer M. Frost , Philip R. Kym
- 申请人： Calico Life Sciences LLC , AbbVie Inc.
- 申请人地址： US CA South San Francisco US IL North Chicago
- 专利权人： Calico Life Sciences LLC,AbbVie Inc.
- 当前专利权人： Calico Life Sciences LLC,AbbVie Inc.
- 当前专利权人地址： US CA South San Francisco US IL North Chicago
- 主分类号： C07D285/10
- IPC分类号： C07D285/10
摘要：
Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.
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