Invention Application
- Patent Title: TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING A BENZOTRIAZOLE MOIETY, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR
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Application No.: US16890765Application Date: 2020-06-02
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Publication No.: US20200291028A1Publication Date: 2020-09-17
- Inventor: Yam B. Poudel , Sanjeev Gangwar , Prasanna Sivaprakasam , Shoshana L. Posy
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Main IPC: C07D473/18
- IPC: C07D473/18 ; A61P37/04
Abstract:
Compounds having a structure according to formula (I) where R1, R2, and R3 are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
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