Invention Application
- Patent Title: TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
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Application No.: US16062680Application Date: 2016-12-14
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Publication No.: US20180362542A1Publication Date: 2018-12-20
- Inventor: Robert John AVERSA , Matthew T. BURGER , Michael Patrick DILLON , Thomas A. DINEEN, Jr. , Rajesh KARKI , Savrithi RAMURTHY , Vivek RAUNIYAR , Richard ROBINSON , Patrick James SARVER
- Applicant: Novartis AG
- International Application: PCT/IB2016/057633 WO 20161214
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D491/044 ; C07D487/04 ; A61P35/00

Abstract:
The present invention provides compounds of Formula (A): (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent, and methods of using the compositions and combinations to treat conditions including cancers.
Public/Granted literature
- US10377770B2 Tricyclic compounds and compositions as kinase inhibitors Public/Granted day:2019-08-13
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