发明申请
- 专利标题: FLOW RATE BALANCED, DYNAMICALLY ADJUSTABLE SHEATH DELIVERY SYSTEM FOR FLOW CYTOMETRY
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申请号: US16030174申请日: 2018-07-09
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公开(公告)号: US20180313742A1公开(公告)日: 2018-11-01
- 发明人: Daniel Nelson Fox , Nathan Michael Gaskill-Fox
- 申请人: Bio-Rad Laboratories, Inc.
- 主分类号: G01N15/14
- IPC分类号: G01N15/14
摘要:
Disclosed is a sheath delivery system that uses a continuous flow of sheath fluid into a pressurized internal reservoir that substantially matches the outflow of sheath fluid through the nozzle of a flow cytometer. A substantially constant level of the sheath fluid is maintained. If the sheath fluid level falls below a desired level, or goes above a desired level, a dampened control system is used to reach the desired level. In addition, air pressure in the pressurized internal container is controlled so that an external sheath container can be removed and refilled with additional sheath fluid without stopping the sheath delivery system 100. Differences in pressure are detected by a droplet camera, which measures the droplet breakoff point to determine the pressure of the sheath fluid in the nozzle.
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