- 专利标题： MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
-
申请号： US15659926申请日： 2017-07-26
-
公开(公告)号： US20180162842A1公开(公告)日： 2018-06-14
- 发明人: Sara S. HADIDA RUAH , Peter D.J. GROOTENHUIS , Fredrick VAN GOOR , Jinglan ZHOU , Brian BEAR , Mark T. MILLER , Jason McCARTNEY , Mehdi Michel Jamel NUMA , Xiaoqing YANG
- 申请人： Vertex Pharmaceuticals Incorporated
- 主分类号： C07D405/12
- IPC分类号： C07D405/12 ; C07D487/04 ; C07B59/00 ; G01N33/68 ; G01N33/50 ; C07D403/12 ; C07D471/04 ; C07D405/14
摘要：
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
公开/授权文献
- US10239867B2 Modulators of ATP-binding cassette transporters 公开/授权日：2019-03-26
信息查询
