Invention Application
- Patent Title: CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS
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Application No.: US15547499Application Date: 2016-01-26
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Publication No.: US20180009853A1Publication Date: 2018-01-11
- Inventor: Ada YONATH , Zohar EYAL , Donna MATZOV , Haim ROZENBERG , Ella ZIMMERMAN , Anat BASHAN
- Applicant: Yeda Research And Development Co. Ltd.
- International Application: PCT/IL2016/050082 WO 20160126
- Main IPC: C07K14/31
- IPC: C07K14/31 ; C07H17/08 ; C07D211/54 ; C07D263/20 ; G06F19/00 ; G06F19/16
Abstract:
A composition-of-matter comprising a crystallized form of a large ribosomal (50S) subunit of a pathogenic bacterium, and the atomic coordinates of the three-dimensional structure thereof are provided herein, as well as methods for crystallizing the same, and using the atomic coordinates of the same to design de novo ligands with high specificity thereto.
Public/Granted literature
- US10556934B2 Crystal structure of the large ribosomal subunit from S. aureus Public/Granted day:2020-02-11
Information query
