A method of beam misalignment detection for wireless communication system with beamforming is proposed. To identify a misaligned beam, a relative beam quality degradation is applied by comparing a dedicated beam quality with a reference beam quality. The reference beam favors similar transmission path as the dedicated beam, and has better mobility robustness. In one embodiment, the reference beam is an associated control beam of the dedicated beam. To detect beam misalignment, a first dedicated beam SINR is compared with a second associated control beam SINR.