发明申请
- 专利标题: BI-SPECIFIC ANTIBODIES AND USES THEREOF
- 专利标题(中): 双特异性抗体及其用途
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申请号: US15123243申请日: 2015-03-02
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公开(公告)号: US20170056523A1公开(公告)日: 2017-03-02
- 发明人: STEVEN R ROFFLER , TIAN-LU CHENG , CHIEN-HAN KAO , BING-MAE CHEN , YU-CHENG SU , HSIN-YI TUNG , Kuo-Hsiang Chuang
- 申请人: ACADEMIA SINICA , KAOHSIUNG MEDICAL UNIVERSITY
- 申请人地址: TW Taipei City TW Kaohsiung City
- 专利权人: ACADEMIA SINICA,KAOHSIUNG MEDICAL UNIVERSITY
- 当前专利权人: ACADEMIA SINICA,KAOHSIUNG MEDICAL UNIVERSITY
- 当前专利权人地址: TW Taipei City TW Kaohsiung City
- 国际申请: PCT/US2015/018365 WO 20150302
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; A61K49/00 ; C07K16/28 ; C07K16/32 ; C07K16/44 ; C07K16/30
摘要:
Disclosed herein is a bi-specific antibody that specifically directs a therapeutic agent to a cancer cell by targeting a tumor antigen of the cancer cell, and thereby suppresses the growth of the cancer or blocking the invasion or metastasis of the cancer. The bi-specific antibody of the present disclosure includes a first antigen binding site that binds to polyethylene glycol (PEG); and a second antigen binding site that binds to a target ligand, such as a tumor antigen.
公开/授权文献
- US10188742B2 Bi-specific antibodies and uses thereof 公开/授权日:2019-01-29
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