发明申请
US20160209350A1 Compositions, Devices, Systems, and Methods for Using a Nanopore
审中-公开
组合物，器件，系统和使用纳米孔的方法
- 专利标题： Compositions, Devices, Systems, and Methods for Using a Nanopore
- 专利标题（中）： 组合物，器件，系统和使用纳米孔的方法
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申请号： US15087734申请日： 2016-03-31
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公开(公告)号： US20160209350A1公开(公告)日： 2016-07-21
- 发明人: Mark A. Akeson , David W. Deamer , William B. Dunbar , Roger Jinteh Arrigo Chen , Noah A. Wilson
- 申请人： The Regents of the University of California
- 主分类号： G01N27/327
- IPC分类号： G01N27/327 ; C12Q1/68 ; G01N27/416 ; C12Q1/54
摘要：
Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.
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