A multi-function lighting system is provided. Multiplex configuration of a lighting module and optical time domain modulation of an electric controlling system are applied to a lighting system which senses environmental conditions to automatically or artificially change a color, a light intensity and a color-temperature of a light to influence people's feelings and moods. The environmental sensing device further feedbacks an information of humidity or temperature so that parameter of optimum light environment can be set accordingly. The lighting module is applied to the design of the lighting system, such that the lighting system can be manufactured in a customization way to meet varied requirements in the landscaping and optical designs, not only reducing the cost and increasing mass production rate but also providing multi-functions including landscaping lighting, ergonomic lighting, display lighting, light communication, plant lighting air purifying, and preservation of fruits and vegetables.