发明申请
US20150225397A1 ARYL AND ARYLALKYL SUBSTITUTED PYRAZOLYL AND PYRIMIDINYL TRICYCLIC ENONES AS ANTIOXIDANT INFLAMMATION MODULATORS
有权
ARYL和ARYLALKYL取代的吡唑并吡啶并吡啶酮作为抗氧化剂的炎症调节剂
- 专利标题: ARYL AND ARYLALKYL SUBSTITUTED PYRAZOLYL AND PYRIMIDINYL TRICYCLIC ENONES AS ANTIOXIDANT INFLAMMATION MODULATORS
- 专利标题(中): ARYL和ARYLALKYL取代的吡唑并吡啶并吡啶酮作为抗氧化剂的炎症调节剂
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申请号: US14604129申请日: 2015-01-23
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公开(公告)号: US20150225397A1公开(公告)日: 2015-08-13
- 发明人: Pamela Donner , Rolf Wagner , Jason Shanley , Howard Heyman , Allan Krueger , Hui-Ju Chen , Michael Rozema , David Grampovnik , Melean Visnick , Eric Anderson , Xin Jiang , Christopher F. Bender , Gary Louis Bolton , Bradley William Caprathe , Chitase Lee , William Howard Roark
- 申请人: AbbVie Inc. , Reata Pharmaceuticals, Inc.
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; C07D231/54 ; C07D413/04 ; C07D403/04 ; C07D417/04 ; C07D239/70 ; C07D401/04
摘要:
The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein R1, R2, R3, R4, R5, R6, m, n, X and Y are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use for the treatment and prevention of diseases such as those associated with oxidative stress and inflammation.
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