Invention Application
US20150133658A1 NEPRILYSIN INHIBITORS 有权
NEPRILYSIN抑制剂

NEPRILYSIN INHIBITORS
Abstract:
In one aspect, the invention relates to compounds having the formula: where R1, R2a, R2b, R3-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
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