发明申请
US20150119270A1 METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN 有权
检测蛋白质单独调节剂的方法

  • 专利标题: METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN
  • 专利标题(中): 检测蛋白质单独调节剂的方法
  • 申请号: US14396494
    申请日: 2013-04-25
  • 公开(公告)号: US20150119270A1
    公开(公告)日: 2015-04-30
  • 发明人: Joshua S. Salafsky
  • 申请人: BIODESY,INC.
  • 国际申请: PCT/US2013/000117 WO 20130425
  • 主分类号: G01N33/542
  • IPC分类号: G01N33/542 G01N33/543 G01N33/68 G01N33/74
METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN
摘要:
The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation
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