发明申请
- 专利标题: METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN
- 专利标题(中): 检测蛋白质单独调节剂的方法
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申请号: US14396494申请日: 2013-04-25
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公开(公告)号: US20150119270A1公开(公告)日: 2015-04-30
- 发明人: Joshua S. Salafsky
- 申请人: BIODESY,INC.
- 国际申请: PCT/US2013/000117 WO 20130425
- 主分类号: G01N33/542
- IPC分类号: G01N33/542 ; G01N33/543 ; G01N33/68 ; G01N33/74
摘要:
The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation
公开/授权文献
- US09395358B2 Methods for detecting allosteric modulators of protein 公开/授权日:2016-07-19
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