发明申请
US20150087825A1 SPIROCYCLIC DIGYDRO-THIAZINE AND DIHYDRO-OXAZINE BACE INHIBITORS, AND COMPOSITIONS AND USES THEREOF
审中-公开
螺环DIGYDRO-THIAZINE和DIHYDRO-OXAZINE BACE抑制剂及其组合物及其用途
- 专利标题： SPIROCYCLIC DIGYDRO-THIAZINE AND DIHYDRO-OXAZINE BACE INHIBITORS, AND COMPOSITIONS AND USES THEREOF
- 专利标题（中）： 螺环DIGYDRO-THIAZINE和DIHYDRO-OXAZINE BACE抑制剂及其组合物及其用途
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申请号： US14556895申请日： 2014-12-01
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公开(公告)号： US20150087825A1公开(公告)日： 2015-03-26
- 发明人: Ying-Zi Xu , Dean R. Artis , Simeon Bowers , Roy K. Hom , Hing L. Sham , Shendong Yuan
- 申请人： Ying-Zi Xu , Dean R. Artis , Simeon Bowers , Roy K. Hom , Hing L. Sham , Shendong Yuan
- 主分类号： C07D513/10
- IPC分类号： C07D513/10
摘要：
Compounds are provided having a structure according to Formula (I): wherein A1, A2, A3, Y, R1, R2, R3, R4, R5, R6, m, n and p are defined herein. Further provided are pharmaceutical compositions including the compounds provided and methods of making and using the compounds and compositions as provided, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.
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