Invention Application
US20150071861A1 POLYMER, CONTRAST AGENT FOR NUCLEAR MAGNETIC RESONANCE ANALYSIS OR MAGNETIC RESONANCE IMAGING USING THE POLYMER, COMPOUND AND METHOD OF NUCLEAR MAGNETIC RESONANCE ANALYSIS AND METHOD OF MAGNETIC RESONANCE IMAGING USING THE POLYMER
审中-公开
聚合物，使用聚合物的核磁共振分析或磁共振成像的对比剂，核磁共振分析的化合物和方法以及使用聚合物的磁共振成像方法
- Patent Title: POLYMER, CONTRAST AGENT FOR NUCLEAR MAGNETIC RESONANCE ANALYSIS OR MAGNETIC RESONANCE IMAGING USING THE POLYMER, COMPOUND AND METHOD OF NUCLEAR MAGNETIC RESONANCE ANALYSIS AND METHOD OF MAGNETIC RESONANCE IMAGING USING THE POLYMER
- Patent Title (中): 聚合物，使用聚合物的核磁共振分析或磁共振成像的对比剂，核磁共振分析的化合物和方法以及使用聚合物的磁共振成像方法
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Application No.: US14395193Application Date: 2013-05-22
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Publication No.: US20150071861A1Publication Date: 2015-03-12
- Inventor: Teruyuki Kondo , Yasuhiro Aoyama , Hisatsugu Yamada , Yoshinori Hasegawa , Hidehito Tochio , Yu Kimura , Masahiro Shirakawa , Fuminori Sugihara , Tetsuya Matsuda , Shinsuke Sando , Masato Minami , Fumio Yamauchi , Tetsuya Yano , Hidetoshi Tsuzuki
- Applicant: CANON KABUSHIKI KAISHA
- Applicant Address: JP Tokyo
- Assignee: CANON KABUSHIKI KAISHA
- Current Assignee: CANON KABUSHIKI KAISHA
- Current Assignee Address: JP Tokyo
- Priority: JP2012-118061 20120523
- International Application: PCT/JP2013/064819 WO 20130522
- Main IPC: A61K49/12
- IPC: A61K49/12 ; C08F30/02
Abstract:
As a substance used as a contrast agent for a method of nuclear magnetic resonance analysis or a method of magnetic resonance imaging, a substance with high selectivity and high sensitivity was demanded. According to the present invention, when a polymer having, in a side chain thereof, a sequence of a 1H—13C—15N, 1H—15N—13C or 1H—13C—13C bond, that is, a structure labeled with stable isotopes of 13C and 15N, is used, the abundance of such a sequence in one molecule can be increased, and hence, high selectivity and higher sensitivity can be attained when used as a contrast agent.
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