发明申请
US20150056105A1 AUTOMATIC SYSTEM FOR SYNTHESIZING 123I-MIBG AND AUTOMATIC DEVICE FOR SYNTHESIZING AND DISPENSING 123I-MIBG COMPRISING THE SAME
有权
用于合成123I-MIBG的自动系统和用于合成和分配包含其的123I-MIBG的自动装置
- 专利标题： AUTOMATIC SYSTEM FOR SYNTHESIZING 123I-MIBG AND AUTOMATIC DEVICE FOR SYNTHESIZING AND DISPENSING 123I-MIBG COMPRISING THE SAME
- 专利标题（中）： 用于合成123I-MIBG的自动系统和用于合成和分配包含其的123I-MIBG的自动装置
-
申请号： US14464461申请日： 2014-08-20
-
公开(公告)号： US20150056105A1公开(公告)日： 2015-02-26
- 发明人: Tsai-Yueh LUO , Te-Sheng LIANG , Ying-Hsia SHIH , Wuu-Jyh LIN
- 申请人： Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
- 优先权： TW102129819 20130820
- 主分类号： B01J19/00
- IPC分类号： B01J19/00 ; B01J19/24 ; A61K51/04
摘要：
The present invention relates to an automatic system for synthesizing iodine-123 meta-iodobenzylguanidine (123I-MIBG), which comprises a first reactor for subjecting radioactive iodine-containing sodium iodide and meta-iodobenzylguanidine (MIBG) sulfate to an iodine-iodine exchange reaction to obtain radioactive iodine labeled MIBG; a purification unit for purifying the iodine labeled MIBG; and a second reactor for substituting a solvent used in purification with a phosphate buffer to obtain a phosphate solution containing 123I-MIBG. The present invention also relates to an automatic device for dispensing 123I-MIBG, which comprises the automatic system for synthesizing 123I-MIBG, a radioactivity measuring unit, and a dispensing and packing unit.
公开/授权文献
信息查询
