发明申请
US20140193863A1 Methods Of Producing 7-Carbon Chemicals Via C1 Carbon Chain Elongation Associated With Coenzyme B Synthesis
有权
通过与辅酶B合成相关的C1碳链伸长率生产7碳化合物的方法
- 专利标题: Methods Of Producing 7-Carbon Chemicals Via C1 Carbon Chain Elongation Associated With Coenzyme B Synthesis
- 专利标题(中): 通过与辅酶B合成相关的C1碳链伸长率生产7碳化合物的方法
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申请号: US14138971申请日: 2013-12-23
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公开(公告)号: US20140193863A1公开(公告)日: 2014-07-10
- 发明人: Adriana Leonora Botes , Alex Van Eck Conradie , Changlin Chen , Paul S. Pearlman
- 申请人: INVISTA North America S.á r.I.
- 申请人地址: US DE Wilmington
- 专利权人: INVISTA North America S.á r.I.
- 当前专利权人: INVISTA North America S.á r.I.
- 当前专利权人地址: US DE Wilmington
- 主分类号: C12P13/00
- IPC分类号: C12P13/00 ; C12P7/42 ; C12P7/18 ; C12P7/44
摘要:
This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming one or two terminal functional groups, each comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the C1 elongation enzymes or homolog associated with coenzyme B biosynthesis.
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