Invention Application
- Patent Title: ANTI-HUMAN HER3 ANTIBODIES AND USES THEREOF
- Patent Title (中): 抗人HER3抗体及其用途
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Application No.: US14118747Application Date: 2012-05-21
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Publication No.: US20140112931A1Publication Date: 2014-04-24
- Inventor: Thierry Chardes , Andre Pelegrin , Christel Larbouret , Nadege Gaborit , Yassamine Lazrek
- Applicant: Thierry Chardes , Andre Pelegrin , Christel Larbouret , Nadege Gaborit , Yassamine Lazrek
- Applicant Address: FR Montpellier Cedex 2 FR Montpellier Cedex 5
- Assignee: UNIVERSITE DE MONTPELLIER 1,CENTRE VAL D'AURELLE - PAUL LAMARQUE
- Current Assignee: UNIVERSITE DE MONTPELLIER 1,CENTRE VAL D'AURELLE - PAUL LAMARQUE
- Current Assignee Address: FR Montpellier Cedex 2 FR Montpellier Cedex 5
- Priority: EP11305607.1 20110519
- International Application: PCT/EP2012/059402 WO 20120521
- Main IPC: C07K16/28
- IPC: C07K16/28

Abstract:
The present invention provides for isolated anti-human-HER3 antibodies or fragments thereof. More particularly the present invention provides an isolated monoclonal antibody that specifically binds to the extracellular domain of HER-3 and competes for binding to the extracellular domain of human HER-3 with the antibody produced obtainable from hybridoma deposited as CNCM-I-4486. The antibodies described in the present invention are useful for the treatment of cancer.
Public/Granted literature
- US09127065B2 Anti-human HER3 antibodies and uses thereof Public/Granted day:2015-09-08
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