- 专利标题： SYSTEMS AND METHODS FOR SINGLE-MOLECULE DETECTION USING NANOPORES
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申请号： US13787341申请日： 2013-03-06
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公开(公告)号： US20130180867A1公开(公告)日： 2013-07-18
- 发明人: Jacob Rosenstein , Kenneth L. Shepard
- 申请人： The Trustees of Columbia University in the City of New York
- 申请人地址： US NY New York
- 专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人： The Trustees of Columbia University in the City of New York
- 当前专利权人地址： US NY New York
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00 ; G01N27/447 ; G01N27/26
摘要：
A system and method for detecting a single-molecule using an integrated circuit which includes at least one membrane having a nanopore located between first and second reservoirs and a low-noise preamplifier having an electrode formed on the surface thereof is provided. The method includes passing a target molecule through the nanopore, and measuring a current through the nanopore to detect the presence of a biomolecular entity, if any.
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