发明申请
US20130131063A1 Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
失效
抑制BCL蛋白与结合伙伴相互作用的化合物和方法
- 专利标题： Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
- 专利标题（中）： 抑制BCL蛋白与结合伙伴相互作用的化合物和方法
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申请号： US13472136申请日： 2012-05-15
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公开(公告)号： US20130131063A1公开(公告)日： 2013-05-23
- 发明人: Alfredo C. Castro , Kristopher M. Depew , Michael J. Grogan , Charles W. Johannes , Edward B. Holson , Brian T. Hopkins , Gregg F. Keaney , Nii O. Koney , Tao Liu , David A. Mann , Marta Nevalainen , Stephane Peluso , Lawrence Blas Perez , Daniel A. Snyder , Thomas T. Tibbitts
- 申请人： Alfredo C. Castro , Kristopher M. Depew , Michael J. Grogan , Charles W. Johannes , Edward B. Holson , Brian T. Hopkins , Gregg F. Keaney , Nii O. Koney , Tao Liu , David A. Mann , Marta Nevalainen , Stephane Peluso , Lawrence Blas Perez , Daniel A. Snyder , Thomas T. Tibbitts
- 申请人地址： US MA Cambridge
- 专利权人： Infinity Pharmaceuticals, Inc.
- 当前专利权人： Infinity Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： C07D261/02
- IPC分类号： C07D261/02 ; C07D417/12 ; A61K31/5377 ; A61K31/454 ; A61K31/496 ; A61K31/42 ; A61K31/422 ; A61K31/427 ; A61K31/4439 ; C07D413/10 ; C07D413/12 ; A61K45/06
摘要：
The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
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