发明申请
- 专利标题： GENETIC SUSCEPTIBILITY VARIANTS ASSOCIATED WITH CARDIOVASCULAR DISEASE
- 专利标题（中）： 与心脏病相关的遗传易感性变异
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申请号： US13451210申请日： 2012-04-19
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公开(公告)号： US20120208709A1公开(公告)日： 2012-08-16
- 发明人: Andrei Manolescu , Anna Helgadottir , Gudmar Thorleifsson
- 申请人： Andrei Manolescu , Anna Helgadottir , Gudmar Thorleifsson
- 申请人地址： IS Reykjavik
- 专利权人： deCODE Genetics ehf.
- 当前专利权人： deCODE Genetics ehf.
- 当前专利权人地址： IS Reykjavik
- 优先权： IS8613 20070221; IS8640 20070430; IS8701 20071221
- 主分类号： C40B20/00
- IPC分类号： C40B20/00 ; C12Q1/68
摘要：
The invention relates to methods of diagnosing susceptibility to cardiovascular disease, including coronary artery disease, MI, abdominal aorta aneurysm, intracranial aneurysm restenosis and peripheral arterial disease, by assessing the presence or absence of alleles of certain polymorphic markers found to be associated with cardiovascular disease. The invention further relates to kits encompassing reagents for assessing such markers, and methods for assessing the probability of response to therapeutic agents and methods using such markers.
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