- 专利标题： MICROBIOLOGICALLY SOUND AND STABLE SOLUTIONS OF GAMMA-HYDROXYBUTYRATE SALT FOR THE TREATMENT OF NARCOLEPSY
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申请号： US13446892申请日： 2012-04-13
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公开(公告)号： US20120202879A1公开(公告)日： 2012-08-09
- 发明人: Harry Cook , Martha Hamilton , Douglas Danielson , Colette Goderstad , Dayton Reardan
- 申请人： Harry Cook , Martha Hamilton , Douglas Danielson , Colette Goderstad , Dayton Reardan
- 申请人地址： US CA Palo Alto
- 专利权人： Jazz Pharmaceuticals, Inc.
- 当前专利权人： Jazz Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Palo Alto
- 主分类号： A61K31/19
- IPC分类号： A61K31/19 ; A61P25/00 ; A61P21/00
摘要：
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorders, including narcolepsy, with these stable formulations of GHB. The present invention also provides methods to treat alcohol and opiate withdrawal, reduced levels of growth hormone, increased intracranial pressure, and physical pain in a patient.
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