Invention Application
- Patent Title: CORNEAL ENDOTHELIAL CELL PROLIFERATION PROMOTER
- Patent Title (中): 角膜内皮细胞增殖促进剂
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Application No.: US13386844Application Date: 2009-07-24
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Publication No.: US20120190621A1Publication Date: 2012-07-26
- Inventor: Yasuhiko Tabata , Shigeru Kinoshita , Noriko Koizumi , Yuji Sakamoto , Naoki Okumura , Hiroaki Takahashi
- Applicant: Yasuhiko Tabata , Shigeru Kinoshita , Noriko Koizumi , Yuji Sakamoto , Naoki Okumura , Hiroaki Takahashi
- Applicant Address: JP Osaka-shi, Osaka JP Uji-shi, Kyoto
- Assignee: SENJU PHARMACEUTICAL CO., LTD.,Yasuhiko TABATA
- Current Assignee: SENJU PHARMACEUTICAL CO., LTD.,Yasuhiko TABATA
- Current Assignee Address: JP Osaka-shi, Osaka JP Uji-shi, Kyoto
- International Application: PCT/JP2009/063624 WO 20090724
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61P27/02
Abstract:
The present invention aims to provide a corneal endothelium cell proliferation accelerator and a therapeutic agent for a disease relating to corneal endothelium damage, which are administered into the anterior chamber. bFGF is released in a sustained manner by forming bFGF sustained-release gelatin hydrogel particles wherein bFGF is carried on gelatin hydrogel. Therefore, the proliferation of corneal endothelium cells can be accelerated persistently by administration of a preparation containing the bFGF sustained-release gelatin hydrogel particles into the anterior chamber, and diseases relating to corneal endothelium damage can be treated.
Public/Granted literature
- US08895508B2 Methods for corneal endothelial proliferation using bFGF sustained-release gelatin hydrogel particles Public/Granted day:2014-11-25
Information query
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