A system for tubular ligation is disclosed. The system may include an anchor designed to advance into a channel and engage the walls of the channel. The anchor may have mechanisms that allow it to securely attach to walls of the channel and pull the channel. The system may also include a body for placement adjacent to the channel to align the anchor with the channel. The anchor and body may be arranged so that subsequent retreat of the anchor toward the body pulls and inverts a portion of the channel. The system may also include an occlusion mechanism for placement about the inverted portion of the channel to seal the channel. The occlusion mechanism may be configured to bias between an open state for placement on the body, and a compressed state for sealing the channel. A method for tubular ligation is also disclosed.