Invention Application
US20120129721A1 URINARY GM2 ACTIVATOR PROTEIN AS A MARKER OF ACUTE RENAL FAILURE OR THE RISK OF DEVELOPING ACUTE RENAL FAILURE
审中-公开
URNARY GM2 ACTIVATOR蛋白作为急性肾衰竭标志或发展急性肾衰竭的风险
- Patent Title: URINARY GM2 ACTIVATOR PROTEIN AS A MARKER OF ACUTE RENAL FAILURE OR THE RISK OF DEVELOPING ACUTE RENAL FAILURE
- Patent Title (中): URNARY GM2 ACTIVATOR蛋白作为急性肾衰竭标志或发展急性肾衰竭的风险
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Application No.: US13322378Application Date: 2009-05-26
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Publication No.: US20120129721A1Publication Date: 2012-05-24
- Inventor: Yaremi Quiros Luis , Laura Ferreira Redondo , Sandra María Sancho Martínez , José Manuel Gonzalez De Buitrago , Francisco Jose Lopez Hernandez , José Miguel Lopez Novoa
- Applicant: Yaremi Quiros Luis , Laura Ferreira Redondo , Sandra María Sancho Martínez , José Manuel Gonzalez De Buitrago , Francisco Jose Lopez Hernandez , José Miguel Lopez Novoa
- Applicant Address: ES SALAMANCA
- Assignee: UNIVERSIDAD DE SALAMANCA
- Current Assignee: UNIVERSIDAD DE SALAMANCA
- Current Assignee Address: ES SALAMANCA
- International Application: PCT/EP09/56381 WO 20090526
- Main IPC: C40B30/04
- IPC: C40B30/04 ; G01N27/26 ; G01N27/447 ; G01N33/567
Abstract:
The invention relates to a method of determining the risk of developing acute renal failure (ARF) in an individual, or of determining an ARF, and a method of predicting the progression of an ARF, by detecting and/or quantifying the protein Ganglioside GM2 Activator Protein (GM2AP). The failure can be due to the administration of at least one nephrotoxic agent, wherein the nephrotoxic agent can be an aminoglycoside antibiotic as for example gentamicin.
Information query
