发明申请
US20120020988A1 Antibodies specifically binding to human TSLPR and methods of use
审中-公开
特异性结合人TSLPR的抗体和使用方法
- 专利标题: Antibodies specifically binding to human TSLPR and methods of use
- 专利标题(中): 特异性结合人TSLPR的抗体和使用方法
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申请号: US13184046申请日: 2011-07-15
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公开(公告)号: US20120020988A1公开(公告)日: 2012-01-26
- 发明人: JOHANNES AUER , MARIA FUENTES , GUY GEORGES , HUBERT KETTENBERGER , HANS-WILLI KRELL , JENS NIEWOEHNER , GEORG TIEFENTHALER
- 申请人: JOHANNES AUER , MARIA FUENTES , GUY GEORGES , HUBERT KETTENBERGER , HANS-WILLI KRELL , JENS NIEWOEHNER , GEORG TIEFENTHALER
- 申请人地址: US NJ NUTLEY
- 专利权人: HOFFMANN-LA ROCHE INC.
- 当前专利权人: HOFFMANN-LA ROCHE INC.
- 当前专利权人地址: US NJ NUTLEY
- 优先权: EP10169728.2 20100715
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12N15/63 ; C12N1/21 ; C12P21/06 ; C12N5/10 ; C12N1/19 ; C07K16/28 ; A61P37/00
摘要:
An antibody specifically binding to human thymic stromal lymphopoietin receptor (TSLPR), characterized in comprising as heavy chain variable domain CDR regions a CDR1 region of SEQ ID NO:2 or 17, a CDR2 region of SEQ ID NO:3 or 10, and CDR3 region of SEQ ID NO:4, and as light chain variable domain CDR regions a CDR1 region of SEQ ID NO:6 or 12, a CDR2 region of SEQ ID NO:7, 13 or 15, and a CDR3 region of SEQ ID NO:8. is useful for the treatment of immunological diseases.
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