发明申请
- 专利标题： HYDRAZONOPYRAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTICS
- 专利标题（中）： 水合唑衍生物及其用作治疗药物
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申请号： US12977794申请日： 2010-12-23
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公开(公告)号： US20110237783A1公开(公告)日： 2011-09-29
- 发明人: Zaihui Zhang , Timothy S. Daynard , Mikhail A. Chafeev , Shisen Wang , Gregory B. Chopiuk , Serguei V. Sviridov
- 申请人： Zaihui Zhang , Timothy S. Daynard , Mikhail A. Chafeev , Shisen Wang , Gregory B. Chopiuk , Serguei V. Sviridov
- 申请人地址： CA Vancouver
- 专利权人： Valocor Therapeutics, Inc.
- 当前专利权人： Valocor Therapeutics, Inc.
- 当前专利权人地址： CA Vancouver
- 主分类号： C07D231/38
- IPC分类号： C07D231/38 ; C07D401/02 ; C07D417/02 ; C07D403/02 ; C07D215/02 ; C07F9/6503 ; C07D401/14 ; C07D217/00 ; C07D413/02
摘要：
Pharmaceutical compositions and compounds are provided. The compounds of the invention demonstrate anti-proliferative activity, and may promote apoptosis in cells lacking normal regulation of cell cycle and death. In one embodiment of the invention, pharmaceutical compositions of the compounds in combination with a physiologically acceptable carrier are provided. The pharmaceutical compositions are useful in the treatment of hyperproliferative disorders, which disorders include tumor growth, lymphoproliferative diseases, angiogenesis. The compounds of the invention are substituted pyrazoles and pyrazolines.
公开/授权文献
- US08445694B2 Hydrazonopyrazole derivatives and their use as therapeutics 公开/授权日：2013-05-21
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