Invention Application
- Patent Title: ALKYNYL ALCOHOLS AS KINASE INHIBITORS
- Patent Title (中): 亚苄基醇作为激酶抑制剂
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Application No.: US12997868Application Date: 2009-06-26
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Publication No.: US20110086834A1Publication Date: 2011-04-14
- Inventor: Guoqing Chen , Timothy D. Cushing , Paul Faulder , Benjamin Fisher , Xiao He , Kexue Li , Zhihong Li , Wen Liu , Lawrence R. Mcgee , Vatee Pattaropong , Jennifer L. Seganish , Youngshook Shin , Zhulun Wang
- Applicant: Guoqing Chen , Timothy D. Cushing , Paul Faulder , Benjamin Fisher , Xiao He , Kexue Li , Zhihong Li , Wen Liu , Lawrence R. Mcgee , Vatee Pattaropong , Jennifer L. Seganish , Youngshook Shin , Zhulun Wang
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- International Application: PCT/US09/03803 WO 20090626
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D413/14 ; C07D403/14 ; C07D401/14 ; C07D417/14 ; C07D413/04 ; C07D403/04 ; C07D409/14 ; C07D491/107 ; C07D498/10 ; C07D473/16 ; C07D487/04 ; C07D407/14 ; C07D239/48 ; C07D471/10 ; C07D495/10 ; C07D487/14 ; A61K31/497 ; A61K31/433 ; A61K31/53 ; A61K31/4439 ; A61K31/427 ; A61K31/52 ; A61K31/5377 ; A61K31/505 ; A61K31/519 ; A61K31/55 ; A61P35/00 ; A61P35/02 ; A61P37/06 ; A61P11/06 ; A61P17/00 ; A61P19/02 ; A61P25/28 ; A61P11/00 ; A61P1/00 ; A61P29/00
Abstract:
Selected compounds are effective for prophylaxis and treatment of inflammation and inflammatory disorders, such as NIK-mediated disorders. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, inflammation and the like.
Information query
IPC分类:
