发明申请
- 专利标题： Fused Thiophene Derivatives as Kinase Inhibitors
- 专利标题（中）： 稠合噻吩衍生物作为激酶抑制剂
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申请号： US12303713申请日： 2007-06-04
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公开(公告)号： US20100305066A1公开(公告)日： 2010-12-02
- 发明人: Rikki Peter Alexander , Stuart Bailey , Stephen Brand , Daniel Christopher Brookings , Julien Alistair Brown , Alan Findlay Haughan , Natasha Kinsella , Christopher Lowe , Stephen Robert Mack , William Ross Pitt , Marianna Dilani Richard , Andrew Sharpe , Laura Jane Tait
- 申请人： Rikki Peter Alexander , Stuart Bailey , Stephen Brand , Daniel Christopher Brookings , Julien Alistair Brown , Alan Findlay Haughan , Natasha Kinsella , Christopher Lowe , Stephen Robert Mack , William Ross Pitt , Marianna Dilani Richard , Andrew Sharpe , Laura Jane Tait
- 申请人地址： BE Brussels
- 专利权人： UCB PHARMA S.A.
- 当前专利权人： UCB PHARMA S.A.
- 当前专利权人地址： BE Brussels
- 优先权： GB0611152.0 20060606
- 国际申请： PCT/GB2007/002051 WO 20070604
- 主分类号： A61K31/695
- IPC分类号： A61K31/695 ; C07D413/04 ; A61K31/5377 ; C07D413/14 ; C07F7/08 ; C07D495/04 ; A61K31/55 ; A61P3/00 ; A61P13/00 ; A61P9/00 ; A61P25/00 ; A61P27/02 ; A61P37/00
摘要：
A series of 5,6-dihydro-1-benzothiophen-7(4H)-one derivatives, and analogues thereof, which are substituted in the 2-position by an optionally substituted morpholin-4-yl moiety, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
公开/授权文献
- US08324204B2 Fused thiophene derivatives as kinase inhibitors 公开/授权日：2012-12-04
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