发明申请
US20100267139A1 OSTEOPONTIN NANOPARTICLE SYSTEM FOR DRUG DELIVERY
审中-公开
用于药物递送的OSTEOPONTIN NANOPARTICLE系统
- 专利标题： OSTEOPONTIN NANOPARTICLE SYSTEM FOR DRUG DELIVERY
- 专利标题（中）： 用于药物递送的OSTEOPONTIN NANOPARTICLE系统
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申请号： US12669112申请日： 2008-07-16
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公开(公告)号： US20100267139A1公开(公告)日： 2010-10-21
- 发明人: Jørgen Kjems , Kenneth Alan Howard , Flemming Besenbacher , Morten Andreasen
- 申请人： Jørgen Kjems , Kenneth Alan Howard , Flemming Besenbacher , Morten Andreasen
- 申请人地址： DK Aarhus C
- 专利权人： AARHUS UNIVERSITET
- 当前专利权人： AARHUS UNIVERSITET
- 当前专利权人地址： DK Aarhus C
- 优先权： DKPA200701054 20070716
- 国际申请： PCT/DK2008/050179 WO 20080716
- 主分类号： C12N5/071
- IPC分类号： C12N5/071 ; C07K17/10 ; C07K16/00 ; B32B5/00 ; C12N15/63
摘要：
The present invention relates to nanoparticles comprising osteopontin and a polymer carrier, preferably a cationic carrier. Preferably, the cationic carrier is chitosan. Osteopontin and/or the cationic carrier may have bioactivity and/or the nanoparticle may comprise an additional component with bioactivity. Such additional bioactive component may e.g. be a siRNA. The nanoparticles of the invention may be used for treatment of bone diseases or inflammatory diseases.
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