发明申请
- 专利标题: MULTISPECIFIC ANTIBODIES COMPRISING FULL LENGTH ANTIBODIES AND SINGLE CHAIN FAB FRAGMENTS
- 专利标题(中): 包含全长抗体和单链片段的多重抗体
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申请号: US12750748申请日: 2010-03-31
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公开(公告)号: US20100256338A1公开(公告)日: 2010-10-07
- 发明人: Ulrich Brinkmann , Peter Bruenker , Rebecca Croasdale , Christian Klein , Erhard Kopetzki , Ekkehard Moessner , Joerg Thomas Regula , Juergen Michael Schanzer , Jan Olaf Stracke , Pabio Umana
- 申请人: Ulrich Brinkmann , Peter Bruenker , Rebecca Croasdale , Christian Klein , Erhard Kopetzki , Ekkehard Moessner , Joerg Thomas Regula , Juergen Michael Schanzer , Jan Olaf Stracke , Pabio Umana
- 优先权: EP09004909.9 20090402
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C07H21/00
摘要:
The present invention relates to multispecific, especially bispecific antibodies comprising full length antibodies and single chain Fab fragments, methods for their production, pharmaceutical compositions containing the antibodies, and uses thereof.
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