发明申请
- 专利标题： METHODS OF USE OF THE TACI/TACI-L INTERACTION
- 专利标题（中）： TACI / TACI-L相互作用的使用方法
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申请号： US12614109申请日： 2009-11-06
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公开(公告)号： US20100196404A1公开(公告)日： 2010-08-05
- 发明人: RAYMOND G. GOODWIN , WANWAN S. DIN
- 申请人： RAYMOND G. GOODWIN , WANWAN S. DIN
- 申请人地址： US CA THOUSAND OAKS
- 专利权人： IMMUNEX CORPORATION
- 当前专利权人： IMMUNEX CORPORATION
- 当前专利权人地址： US CA THOUSAND OAKS
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12N5/02 ; A61P19/02 ; A61P25/00 ; A61P29/00
摘要：
The invention discloses a novel interaction between a TNF receptor (TACI) and its interacting ligand (TACI-L). Also disclosed are methods of screening candidate molecules to determine potential antagonists and agonists of the TACI/TACI-L interaction. The use of the antagonists and agonists as therapeutics to treat autoimmune diseases, inflammation, and to inhibit graft vs. host rejections is further disclosed.
公开/授权文献
- US08133976B2 Methods of use of the TACI/TACI-L interaction 公开/授权日：2012-03-13
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