发明申请
- 专利标题: PREVENTIVE OR THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASES
- 专利标题(中): 预防或治疗炎症性皮肤病的治疗药物
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申请号: US12449371申请日: 2008-12-17
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公开(公告)号: US20100130475A1公开(公告)日: 2010-05-27
- 发明人: Tomohisa Ninomiya , Takashi Shishikura , Mitsuhiro Uchida , Sho Takahata , Yukari Hoshina , Ken-ichi Kawano
- 申请人: Tomohisa Ninomiya , Takashi Shishikura , Mitsuhiro Uchida , Sho Takahata , Yukari Hoshina , Ken-ichi Kawano
- 专利权人: MEIJI SEIKA KAISHA
- 当前专利权人: MEIJI SEIKA KAISHA
- 优先权: JP2007-326543 20071218
- 国际申请: PCT/JP2008/072999 WO 20081217
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61P1/00
摘要:
The present invention relates to a pharmaceutical composition for preventing or treating inflammatory bowel diseases, which comprises 7,8-dimethoxy-4(5H),10-dioxo-1H-1,2,3-triazolo[4,5-c][1]benzoazepine, a prodrug thereof, preferably 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzoazepine as a prodrug, or a pharmaceutically acceptable salt thereof. The pharmaceutical composition according to the present invention is effective in the prophylaxis and therapy of the inflammatory bowel diseases and has few side effects. Particularly, the pharmaceutical composition according to the present invention may exhibit strong prophylactic and therapeutic effects even on severe cases having resistance to the conventional therapeutics.
公开/授权文献
- US07858612B2 Therapeutic agent for inflammatory bowel diseases 公开/授权日:2010-12-28
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