发明申请
US20100081782A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME
有权
用于可水解产品的ARYL碳酸酯低聚物和包含其的原料
- 专利标题: ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME
- 专利标题(中): 用于可水解产品的ARYL碳酸酯低聚物和包含其的原料
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申请号: US12622645申请日: 2009-11-20
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公开(公告)号: US20100081782A1公开(公告)日: 2010-04-01
- 发明人: Nnochiri N. Ekwuribe , Amy L. Odenbaugh
- 申请人: Nnochiri N. Ekwuribe , Amy L. Odenbaugh
- 主分类号: C08G77/02
- IPC分类号: C08G77/02 ; C08G65/40 ; C08G63/06 ; C08G65/38 ; C08G73/10 ; C08G75/18
摘要:
The present invention provides a compound having a formula: where R1 is selected from the group consisting of alkyl, CH2(OC2H4)OCH3, and —(OC2H4)OCH3; n is 0-4; Olig is an oligomer having a formula: -L-O-PAGR.R2]q where L is a optional linker moiety selected from the group consisting of —CH2O—, —CH2OX—, —OX—, —C(O)—, —C(O)X, —NH—, —NHC(O)—, —XNHC(O)—, —NHC(O)X—, —C(O)NH—, —C(O)NHX—, and where X is alky1-6 or is not present, Y is N or O or is not present, and R3 is alkyl1-6; PAG is a linear or branched polyalkylene glycol moiety; R2 is an alkyl1-22 capping moiety if X is present or alkyl2-22 if X is not present; and q is a number from 1 to the maximum number of branches on PAG; and m is 1-5.
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