发明申请
US20100050279A1 HIGH EFFICIENCY FLP SITE-SPECIFIC RECOMBINATION IN MAMMALIAN CELLS USING AN OPTIMIZED FLP GENE
有权
使用优化的FLP基因在马马里亚细胞中的高效FLP位点特异性重组
- 专利标题: HIGH EFFICIENCY FLP SITE-SPECIFIC RECOMBINATION IN MAMMALIAN CELLS USING AN OPTIMIZED FLP GENE
- 专利标题(中): 使用优化的FLP基因在马马里亚细胞中的高效FLP位点特异性重组
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申请号: US12307418申请日: 2007-06-21
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公开(公告)号: US20100050279A1公开(公告)日: 2010-02-25
- 发明人: Christopher Raymond , Philippe Soriano
- 申请人: Christopher Raymond , Philippe Soriano
- 国际申请: PCT/US07/14482 WO 20070621
- 主分类号: A01K67/027
- IPC分类号: A01K67/027 ; A01K67/033 ; C07H21/00 ; C12N5/00 ; C12N5/07 ; C12N15/63
摘要:
The present invention provides an optimized FLP site-specific recombinase coding sequence and methods for its use. This genetically engineered FLP gene displays a marked increase in recombination efficiency compared to the native FLP gene and is therefore useful in a wide array of molecular applications.
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