发明申请
US20100029596A1 METHOD OF TREATING OR PREVENTING OSTEOPOROSIS COMPRISING ADMINISTERING TO A PATIENT IN NEED THEREOF AN EFFECTIVE AMOUNT OF PHARMACUETICAL COMPOSITION COMPRISING BENZAMIDINE DERIVATIVE OR IT'S SALT, AND BISPHOSPHONATE
失效
治疗或预防包括对需要治疗的患者的OSTEOPOSOSIS的方法有效量的包含苄胺衍生物或其盐的药物组合物和二磷酸盐
- 专利标题： METHOD OF TREATING OR PREVENTING OSTEOPOROSIS COMPRISING ADMINISTERING TO A PATIENT IN NEED THEREOF AN EFFECTIVE AMOUNT OF PHARMACUETICAL COMPOSITION COMPRISING BENZAMIDINE DERIVATIVE OR IT'S SALT, AND BISPHOSPHONATE
- 专利标题（中）： 治疗或预防包括对需要治疗的患者的OSTEOPOSOSIS的方法有效量的包含苄胺衍生物或其盐的药物组合物和二磷酸盐
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申请号： US12533842申请日： 2009-07-31
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公开(公告)号： US20100029596A1公开(公告)日： 2010-02-04
- 发明人: Jei Man RYU , Jin Soo Lee , Yun-Ha Hwang , Young G. Jin , Ki Y. Kim
- 申请人： Jei Man RYU , Jin Soo Lee , Yun-Ha Hwang , Young G. Jin , Ki Y. Kim
- 申请人地址： KR Seoul
- 专利权人： Dong Wha Pharm, Co. Ltd.
- 当前专利权人： Dong Wha Pharm, Co. Ltd.
- 当前专利权人地址： KR Seoul
- 主分类号： A61K31/6615
- IPC分类号： A61K31/6615 ; A61P19/10
摘要：
The present invention provides a method of treating or preventing osteoporosis comprising administering to a patient in need thereof an effective amount of pharmaceutical composition comprising benzamidine derivative or its salt, and bisphosphonate for the purpose of using simultaneously, separately, or sequentially as active ingredients. As a prophylactic or therapeutic composition for osteoporosis, the combination treatment of the benzamidine derivative and the bisphosphonate compound exhibits excellent inhibitory effect on osteoclast differentiation than the total effect of each individual treatment, thereby being used for the prevention or treatment of osteoporosis.
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