发明申请
US20090191220A1 METHODS FOR THE DIAGNOSIS AND TREATMENT OF CRITICALLY ILL PATIENTS WITH ENDOTHELIN, ENDOTHELIN AGONISTS AND ADRENOMEDULLIN ANTAGONISTS
有权
用内皮素，内皮素激素和ADRENOMEDULLIN ANTAGONISTS诊断和治疗关键病人的方法
- 专利标题： METHODS FOR THE DIAGNOSIS AND TREATMENT OF CRITICALLY ILL PATIENTS WITH ENDOTHELIN, ENDOTHELIN AGONISTS AND ADRENOMEDULLIN ANTAGONISTS
- 专利标题（中）： 用内皮素，内皮素激素和ADRENOMEDULLIN ANTAGONISTS诊断和治疗关键病人的方法
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申请号： US12364911申请日： 2009-02-03
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公开(公告)号： US20090191220A1公开(公告)日： 2009-07-30
- 发明人: Andreas BERGMANN , Joachim Struck , Nils G. Morgenthaler
- 申请人： Andreas BERGMANN , Joachim Struck , Nils G. Morgenthaler
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; G01N33/68 ; C12Q1/02 ; G01N33/543
摘要：
The ratio of concentrations of pro-adrenomedullin (pro-ADM)/pro-endothelin (pro-END) immunoreactivity in body fluids of critically ill patients is used as for the diagnosis, course control and prognosis, including an assessment of the mortality risk, of severe life threatening diseases. Further, a treatment of critically ill patients having high levels of pro-ADM but insufficient levels of pro-END immunoreactivities with a medicament comprising vasoconstrictive endothelin or its precursors, and/or endothelin agonists or adrenomedullin antagonists is provided.
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