Invention Application
US20090163453A1 Prevention and Treatment of Gastrointestinal and Bladder Disorders Associated with Chemotherapy or Radiation Therapy Using Active Vitamin D Compounds
审中-公开
使用活性维生素D化合物预防和治疗与化疗或放射治疗相关的胃肠道和膀胱疾病
- Patent Title: Prevention and Treatment of Gastrointestinal and Bladder Disorders Associated with Chemotherapy or Radiation Therapy Using Active Vitamin D Compounds
- Patent Title (中): 使用活性维生素D化合物预防和治疗与化疗或放射治疗相关的胃肠道和膀胱疾病
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Application No.: US11992300Application Date: 2006-09-26
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Publication No.: US20090163453A1Publication Date: 2009-06-25
- Inventor: John G. Curd , Bradford S. Goodwin , Jeffrey L. Cleland
- Applicant: John G. Curd , Bradford S. Goodwin , Jeffrey L. Cleland
- Applicant Address: US CA South San Francisco
- Assignee: Novacea Inc.
- Current Assignee: Novacea Inc.
- Current Assignee Address: US CA South San Francisco
- International Application: PCT/US06/37246 WO 20060926
- Main IPC: A61K31/593
- IPC: A61K31/593 ; A61K31/59 ; A61P35/00 ; A61P35/02
Abstract:
The present invention relates to a method for preventing, treating, or ameliorating gastrointestinal and bladder disorders in a patient receiving a chemotherapy or radiation therapy comprising administering to the patient a therapeutically effective amount of active vitamin D compound or a mimic thereof. According to the invention, the active vitamin D compound or a mimic thereof may be administered by high dose pulse administration so that high doses of the active vitamin D compound or a mimic thereof can be administered to an animal without inducing severe symptomatic hypercalcemia.
Information query
