发明申请
- 专利标题: FORMULATION HAVING ACCURATE DOSE-DIVIDING FUNCTION
- 专利标题(中): 具有精确剂量分配功能的配方
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申请号: US12063721申请日: 2006-08-17
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公开(公告)号: US20090110726A1公开(公告)日: 2009-04-30
- 发明人: Masahiko Narasaki , Tomoya Akutagawa , Reiko Oku
- 申请人: Masahiko Narasaki , Tomoya Akutagawa , Reiko Oku
- 申请人地址: JP Chiyoda-ku, Tokyo
- 专利权人: TEIJIN PHARMA LIMITED
- 当前专利权人: TEIJIN PHARMA LIMITED
- 当前专利权人地址: JP Chiyoda-ku, Tokyo
- 优先权: JP2005-237369 20050818
- 国际申请: PCT/JP2006/316542 WO 20060817
- 主分类号: A61K9/44
- IPC分类号: A61K9/44 ; B29C43/02
摘要:
The present invention provides a tablet comprising a plurality of drug-containing parts and at least one connecting part adhered to the drug-containing parts, and having a scored line capable of dividing the whole tablet on the connecting part; particularly, a coated tablet in which a connecting part and a coating layer have the same or different drug release controlling functions; a tablet having an insoluble coating on a drug-containing part having a scored line, wherein the drug-containing part has a structure or composition such that the drug is substantially released after the tablet is divided along the scored line and then ingested; and a tablet comprising a plurality of drug-containing parts and at least one connecting part adhered to the drug-containing parts, wherein at least two drug-containing parts have different compositions.In addition, the present invention provides a method of manufacturing a tablet, wherein a column comprising a plurality of columnar pharmaceutical composition layers having the same cross-section and laminated in the axial direction of the column is compression molded and then compression molded in a direction different from the axial direction of the column.
公开/授权文献
- US09028867B2 Formulation having accurate dose-dividing function 公开/授权日:2015-05-12
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