发明申请
US20080167385A1 Crystal Structure of Human Proliferating Cell Nuclear Antigen (Pcna) and Uses Thereof
审中-公开
人类增殖细胞核抗原(Pcna)的晶体结构及其用途
- 专利标题: Crystal Structure of Human Proliferating Cell Nuclear Antigen (Pcna) and Uses Thereof
- 专利标题(中): 人类增殖细胞核抗原(Pcna)的晶体结构及其用途
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申请号: US11596149申请日: 2005-05-10
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公开(公告)号: US20080167385A1公开(公告)日: 2008-07-10
- 发明人: George Kontopidis , Daniella I. Zheleva , Campbell McInnes , Peter Martin Fischer , Malcolm Douglas Walkinshaw
- 申请人: George Kontopidis , Daniella I. Zheleva , Campbell McInnes , Peter Martin Fischer , Malcolm Douglas Walkinshaw
- 优先权: GB0410498.0 20040511
- 国际申请: PCT/GB05/01764 WO 20050510
- 主分类号: A61K47/00
- IPC分类号: A61K47/00 ; C07K14/00 ; G01N33/566 ; C40B30/04 ; G06G7/00 ; C12N5/06 ; A61P43/00
摘要:
The present invention relates to crystals comprising human PCNA, and methods and assays for designing and identifying small molecule PCNA inhibitors using said crystals.
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