Invention Application
US20080058369A1 Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors 失效
吡唑并[3,4-b]吡啶化合物及其作为PDE4抑制剂的用途

Pyrazolo[3,4-b]pyridine compounds, and their use as PDE4 inhibitors
Abstract:
The invention provides N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}-4-({8-[(2-hydroxyethyl)(methyl)amino]octanoyl}amino)benzamide, whose formula is , or a salt thereof, such as the monohydrochloride salt thereof. The invention also provides the use of the compound or salt as inhibitors of phosphodiesterase type IV (PDE4) and/or for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, or rhinitis (e.g. allergic and/or non-allergic rhinitis).
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