发明申请
US20070270484A1 3'-N-Substituted-3-O-Substituted Erythronolide a Derivatives
审中-公开
3'-N-取代的3-O-取代的红霉素衍生物
- 专利标题： 3'-N-Substituted-3-O-Substituted Erythronolide a Derivatives
- 专利标题（中）： 3'-N-取代的3-O-取代的红霉素衍生物
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申请号： US10573275申请日： 2003-09-25
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公开(公告)号： US20070270484A1公开(公告)日： 2007-11-22
- 发明人: Biswajit Das , Mohammad Salman , Sachin Shelke , Atul Hajare , Sanjay Talukdar , Sujata Rathy , Arani Pal , Ashok Rattan
- 申请人： Biswajit Das , Mohammad Salman , Sachin Shelke , Atul Hajare , Sanjay Talukdar , Sujata Rathy , Arani Pal , Ashok Rattan
- 国际申请： PCT/IB03/04166 WO 20030925
- 主分类号： A61K31/7048
- IPC分类号： A61K31/7048 ; A61P31/04 ; C07H17/08
摘要：
This invention generally relates to macrolides, more particularly, the invention relates to 3-N-substituted-3-O-substituted erythronolide A derivatives, which are antibacterial agents effective against gram positive or gram negative bacteria and atypical pathogens. The compounds of this invention are more particularly effective against Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Haemophilus influenzae. The invention also relates to a process for the preparation of the compounds of the present invention, pharmaceutical compositions containing the compounds of the present invention and the methods for treating bacterial infection.
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