- 专利标题: Neural stem cells and use thereof for brain tumor therapy
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申请号: US11546726申请日: 2006-10-12
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公开(公告)号: US20070031391A1公开(公告)日: 2007-02-08
- 发明人: Evan Snyder , Xandra Breakefield , Karen Aboody , Ulrich Herrlinger , William Lynch
- 申请人: Evan Snyder , Xandra Breakefield , Karen Aboody , Ulrich Herrlinger , William Lynch
- 申请人地址: US MA Boston US MA Charlestown US OH Rootstown
- 专利权人: Children's Medical Center Corporation,The General Hospital Corporation,Northeastern Ohio Universities College of Medicine
- 当前专利权人: Children's Medical Center Corporation,The General Hospital Corporation,Northeastern Ohio Universities College of Medicine
- 当前专利权人地址: US MA Boston US MA Charlestown US OH Rootstown
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N5/08
摘要:
The present invention is based upon a surprising finding that stem cells, more particularly neural stem cells, can migrate throughout a brain tumor and track metastatic brain tumor cells. The invention provides a method for treating brain tumors by administering genetically engineered neural stem cells in an individual affected by brain tumors. The invention also provides a method of preparing genetically engineered neural stem cells and a composition comprising genetically engineered neural stem cells in a pharmaceutically acceptable carrier.
公开/授权文献
- US07655224B2 Neural stem cells and use thereof for brain tumor therapy 公开/授权日:2010-02-02
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