知搜-全球专利检索

  1. 登录
  2. 注册
发明申请
US20070021448A1 Treating an inflammatory disorder or inhibiting respiratory burst in adherent neutrophils with chemical inhibitors of neutrophil activation 失效
用嗜中性粒细胞活化化学抑制剂治疗粘连嗜中性粒细胞炎症性疾病或抑制呼吸爆发

  • 专利标题： Treating an inflammatory disorder or inhibiting respiratory burst in adherent neutrophils with chemical inhibitors of neutrophil activation
  • 专利标题（中）： 用嗜中性粒细胞活化化学抑制剂治疗粘连嗜中性粒细胞炎症性疾病或抑制呼吸爆发
  • 申请号： US10575683
    申请日： 2004-10-14
  • 公开(公告)号： US20070021448A1
    公开(公告)日： 2007-01-25
  • 发明人: Hyunsil Han , Gang Lin , Carl Nathan
  • 申请人： Hyunsil Han , Gang Lin , Carl Nathan
  • 国际申请： PCT/US04/33914 WO 20041014
  • 主分类号： A61K31/519
  • IPC分类号： A61K31/519 ;  A61K31/4709 ;  A61K31/428 ;  A61K31/4152
Treating an inflammatory disorder or inhibiting respiratory burst in adherent neutrophils with chemical inhibitors of neutrophil activation
摘要：
The present invention relates to a method of treating an inflammatory disorder in a subject with an effective amount of compound having the general formula (I) as described in the present application, under conditions effective to treat the inflammatory disorder. The present invention also relates to a method of inhibiting respiratory burst in neutrophils without or inhibiting degranulation in or bacterial killing by the neutrophils by contacting neutrophils with the compounds described above.
摘要（中）：

本发明涉及在有效治疗炎症性疾病的条件下，用有效量的本申请所述通式（I）的化合物治疗受试者的炎症性疾病的方法。 本发明还涉及一种通过使嗜中性粒细胞与上述化合物接触而抑制嗜中性粒细胞呼吸爆发而不抑制或抑制嗜中性粒细胞脱颗粒或细菌性杀伤的方法。

公开/授权文献
信息查询
Global Dossier Espacenet
0/0