发明申请
US20070014725A1 Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy
审中-公开
大环金属配合物与生物分子的共轭物及其用于生产核磁共振诊断和放射诊断以及放射治疗剂的用途
- 专利标题： Conjugates of macrocyclic metal complexes with biomolecules and their use for the production of agents for NMR diagnosis and radiodiagnosis as well as radiotherapy
- 专利标题（中）： 大环金属配合物与生物分子的共轭物及其用于生产核磁共振诊断和放射诊断以及放射治疗剂的用途
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申请号： US11390414申请日： 2006-03-28
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公开(公告)号： US20070014725A1公开(公告)日： 2007-01-18
- 发明人: Johannes Platzek , Heribert Schmitt-Willich , Gunther Michl , Thomas Frenzel , Detlev Sulzle , Hans Bauer , Bernd Raduchel , Hanns-Joachim Weinmann , Heiko Schirmer
- 申请人： Johannes Platzek , Heribert Schmitt-Willich , Gunther Michl , Thomas Frenzel , Detlev Sulzle , Hans Bauer , Bernd Raduchel , Hanns-Joachim Weinmann , Heiko Schirmer
- 优先权： DE10135355.3 20010720
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; A61K49/10 ; C07K14/47 ; C07F5/00
摘要：
The invention relates to conjugates that consist of macrocyclic metal complexes with biomolecules and their production. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as as agents for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
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