发明申请
- 专利标题： Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
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申请号： US11397055申请日： 2006-04-04
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公开(公告)号： US20060264483A1公开(公告)日： 2006-11-23
- 发明人: Daniel Getman , Gary DeCrescenzo , John Freskos , Michael Vazquez , James Sikorski , Balekudru Devadas , Srinivasan Nagarajan , Joseph McDonald
- 申请人： Daniel Getman , Gary DeCrescenzo , John Freskos , Michael Vazquez , James Sikorski , Balekudru Devadas , Srinivasan Nagarajan , Joseph McDonald
- 申请人地址： US IL Chicago
- 专利权人： G.D. Searle & Co.
- 当前专利权人： G.D. Searle & Co.
- 当前专利权人地址： US IL Chicago
- 主分类号： A61K31/428
- IPC分类号： A61K31/428 ; A61K31/423 ; A61K31/4184 ; A61K31/343 ; C07D417/02 ; C07D277/62 ; C07D263/60 ; C07D235/04
摘要：
Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
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