Disclosed is an oxygen delivery device for regulating the flow of oxygen from an oxygen source to a respiratory cannula located on the face of a patient. A host controller coupled to the oxygen delivery device accepts an input from a medical monitor relating to the blood oxygen saturation percentage of the patient. The host controller then regulates the rate of oxygen supplied to the patient based in part upon the blood oxygen saturation percentage of the patient. A high rate of oxygen is supplied to the patient when the controller detects a blood oxygen saturation level below a predetermined percentage and a low rate of oxygen is supplied when the controller detects a blood oxygen saturation level above a predetermined percentage in an order to minimize wasted oxygen.