发明申请
- 专利标题: N-cyclic sulfonamido inhibitors of gamma secretase
- 专利标题(中): γ-分泌酶的N-环状磺酰胺抑制剂
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申请号: US11133738申请日: 2005-05-20
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公开(公告)号: US20060035884A1公开(公告)日: 2006-02-16
- 发明人: Martin Neitzel , Jennifer Marugg
- 申请人: Martin Neitzel , Jennifer Marugg
- 申请人地址: US CA South San Francisco
- 专利权人: Elan Pharmaceuticals, Inc.
- 当前专利权人: Elan Pharmaceuticals, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07D211/08
- IPC分类号: C07D211/08 ; A61K31/55
摘要:
The invention provides N-cyclic sulfonamido compounds for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula I, wherein R4, R5, R6, R7, and R8, are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I as well as methods of treating cognitive disorders, including Alzheimer's disease using compounds of Formula I.
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