发明申请
US20060035884A1 N-cyclic sulfonamido inhibitors of gamma secretase 审中-公开
γ-分泌酶的N-环状磺酰胺抑制剂

N-cyclic sulfonamido inhibitors of gamma secretase
摘要:
The invention provides N-cyclic sulfonamido compounds for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula I, wherein R4, R5, R6, R7, and R8, are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I as well as methods of treating cognitive disorders, including Alzheimer's disease using compounds of Formula I.
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